Publications

Title Yearsort ascending
Structural Characterization of an Unprecedented Lectin-like Antitumoral anti-MUC1 Antibody 2020
Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase 2020
Synthesis, Biological evaluation, in silico modeling and Crystallisation of novel small monocationic molecules with potent antiproliferative activity by dual mechanism 2020
Ser and Thr Acceptor Preferences of the GalNAc-Ts Vary Among Isoenzymes to Modulate Mucin Type O-Glycosylation 2020
Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases. 2019
Anti-tumoral potential of a human granulysin-based, CEA-targeted cytolytic immunotoxin 2019
Polypeptide GalNAc-Ts: from redundancy to specificity. 2019
Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage. 2019
A perspective on structural and mechanistic aspects of protein O-fucosylation. 2018
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4 2018
Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts. 2018
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins. 2018
Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition. 2018
Inhibitors against Fungal Cell Wall-remodelling Enzymes. ChemMedchem, 2018
Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutase. 2018
Site-Specific O-Glycosylation of Low-Density Lipoprotein Related Receptors Enhance Ligand Interactions. 2018
Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions. 2018
Luteolin can directly inhibit ppGalNAc-Ts and selectively reduce mucin-type O-glycosylation on amyloid precursor protein. 2017
The interdomain flexible linker of the polypeptide GalNAc transferases (GalNAc-Ts) dictates their long-range glycosylation preferences. 2017
NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity. 2017

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