Institute of Biocomputation and Physics of Complex Systems (BIFI) (UZ)
Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) (UZ)
Research interests:
Biophysical study (conformational landscape, interactions and fucntion) of pharmacological targets and proteins with biotechnological and biomedical relevance by spectroscopy and calorimetry
Identification of bioactive compounds able to modulate the function of pharmacological targets and proteins with biotechnological and biomedical relevance by experimental molecular screening
Development of experimental methodologies in calorimetry (ITC and DSC) for studying biomolecular interactions na dprotein folding and stability
Competences:
Structural stability of proteins
Protein interactions
Protein ligand identification
Analysis of complex biological interactions (cooperativity, allostery)
Facilities and techniques:
High sensitivity biological calorimetry
Experimental molecular screening
Protocols and methodologies for studying biomolecular interactions
Keywords:
Biophysics, Biotechnology, Protein stability and folding, Protein interactions, Calorimetry, Molecular screening, Drug discovery, Biomarkers